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Inhibition of host cell invasion and intracellular replication of Trypanosoma cruzi by N,N'-bis(benzyl)-substituted polyamine analogs.

We studied the effects of two N,N'-bis(benzyl)-substituted polyamine analogs on the capacities of Trypanosoma cruzi to invade and multiply within a mammalian host cell. At concentrations as low as 1 microM, these compounds reduced significantly the infectivity of the parasite for rat heart myoblasts...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Majumder, S, Kierszenbaum, F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8257150/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.10.2235
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