Influence of rifampin on fleroxacin pharmacokinetics.

Staphylococcus aureus infections have been successfully treated in animal models with the combination of fleroxacin and rifampin. We studied the influence of rifampin, a potent cytochrome P-450 inducer, on the pharmacokinetics and biotransformation of fleroxacin in 14 healthy young male volunteers....

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Bibliographic Details
Main Authors: Schrenzel, J, Dayer, P, Leemann, T, Weidekamm, E, Portmann, R, Lew, D P
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC192240/
https://ncbi.nlm.nih.gov/pubmed/8257135
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