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Pharmacokinetics of [14C]FCE 22891, a penem antibiotic, following oral administration to healthy volunteers.

FCE 22891 is a prodrug of the penem antibiotic FCE 22101 and is suitable for oral administration. The pharmacokinetics of FCE 22891 were investigated in four healthy male volunteers following the oral administration of 500 mg of [14C]FCE 22891. Levels of radioactivity in plasma were always higher an...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Efthymiopoulos, C, Strolin Benedetti, M, Sassella, D, Boobis, A, Davies, D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.9.1958
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