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Identification and characterization of a cell membrane nucleic acid channel

We have identified a 45-kDa protein purified from rat renal brush border membrane that binds short single-stranded nucleic acid sequences. This activity was purified, reconstituted in proteoliposomes, and then fused with model planar lipid bilayers. In voltage-clamp experiments, the reconstituted 45...

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Autores principales: Hanss, Basil, Leal-Pinto, Edgar, Bruggeman, Leslie A., Copeland, Terry D., Klotman, Paul E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC19214/
https://ncbi.nlm.nih.gov/pubmed/9465118
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