Incorporation of functional human immunodeficiency virus type 1 integrase into virions independent of the Gag-Pol precursor protein.

Retroviral integrase (IN) is expressed and incorporated into virions as part of the Gag-Pol polyprotein precursor. IN catalyzes integration of the proviral DNA into host cell chromosomes during the early stages of the virus life cycle, and as a component of Gag-Pol, it is involved in virion morphoge...

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Pubblicato in:	J Virol
Autori principali:	Liu, H, Wu, X, Xiao, H, Conway, J A, Kappes, J C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7704-7710.1997
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