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The formation of intramolecular disulfide bridges is required for induction of the Sindbis virus mutant ts23 phenotype.

The Sindbis virus envelope protein spike is a hetero-oligomeric complex composed of a trimer of glycoprotein E1-E2 heterodimers. Spike assembly is a multistep process which occurs in the endoplasmic reticulum (ER) and is required for the export of E1 from the ER. PE2 (precursor to E2), however, can...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Carleton, M, Brown, D T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192120/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311853/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7696-7703.1997
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