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Insulin-like growth factor-1 content and pattern of expression correlates with histopathologic grade in diffusely infiltrating astrocytomas.

Studies of experimental tumorigenesis have strongly implicated signaling of the insulin-like growth factor 1 (IGF-1) as a key component in astrocytic neoplasia; however, its role in the growth of low-grade and malignant human tumors is not well understood. Correlative analyses of IGF-1, p53, and Ki-...

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Detalhes bibliográficos
Main Authors: Hirano, H., Lopes, M. B., Laws, E. R., Asakura, T., Goto, M., Carpenter, J. E., Karns, L. R., VandenBerg, S. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920755/
https://ncbi.nlm.nih.gov/pubmed/11550306
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