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Gene-environment interactions in sarcoidosis: challenge and opportunity

Susceptibility to most human diseases is polygenic, with complex interactions between functional polymorphisms of single genes governing disease incidence, phenotype, or both. In this context, the contribution of any discrete gene is generally modest for a single individual, but may confer substanti...

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Detalhes bibliográficos
Main Authors: Culver, Daniel A., Newman, Lee S., Kavuru, Mani S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920704/
https://ncbi.nlm.nih.gov/pubmed/17560304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clindermatol.2007.03.005
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