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A Unique Role for Nonmuscle Myosin Heavy Chain IIA in Regulation of Epithelial Apical Junctions

The integrity and function of the epithelial barrier is dependent on the apical junctional complex (AJC) composed of tight and adherens junctions and regulated by the underlying actin filaments. A major F-actin motor, myosin II, was previously implicated in regulation of the AJC, however direct evid...

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Main Authors: Ivanov, Andrei I., Bachar, Moshe, Babbin, Brian A., Adelstein, Robert S., Nusrat, Asma, Parkos, Charles A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2007
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920554/
https://ncbi.nlm.nih.gov/pubmed/17668046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000658
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