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Increased sensitivity of Candida albicans cells accumulating 14 alpha-methylated sterols to active oxygen: possible relevance to in vivo efficacies of azole antifungal agents.

The sensitivity of Candida albicans cells to killing by hydrogen peroxide was found to increase markedly when they were grown in the presence of sub-growth-inhibitory concentrations of the azole drug clotrimazole (CTZ). A superoxide anion-generating system consisting of xanthine and xanthine oxidase...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Shimokawa, O, Nakayama, H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329623/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.8.1626
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