טוען...
The −11A of promoter DNA and two conserved amino acids in the melting region of σ(70) both directly affect the rate limiting step in formation of the stable RNA polymerase-promoter complex, but they do not necessarily interact
Formation of the stable, strand separated, ‘open’ complex between RNA polymerase and a promoter involves DNA melting of approximately 14 base pairs. The likely nucleation site is the highly conserved −11A base in the non-template strand of the −10 promoter region. Amino acid residues Y430 and W433 o...
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| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1919498/ https://ncbi.nlm.nih.gov/pubmed/17567604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm431 |
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