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Minor differences in haplotype frequency estimates can produce very large differences in heterogeneity test statistics
BACKGROUND: Tests for association between a haplotype and disease are commonly performed using a likelihood ratio test for heterogeneity between case and control haplotype frequencies. Using data from a study of association between heroin dependence and the DRD2 gene, we obtained estimated haplotype...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1919392/ https://ncbi.nlm.nih.gov/pubmed/17597526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-38 |
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