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Impact of phase II trials with progression-free survival as end-points on survival-based phase III studies in patients with anaplastic gliomas
BACKGROUND: To assess progression-free survival (PFS) as the appropriate end-point for phase II trials for anaplastic gliomas (AGs) and to determine the impact of PFS on survival-based phase III trials. METHODS: Combined data from 16 phase II studies (N = 529 patients) were analyzed to determine pro...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1919386/ https://ncbi.nlm.nih.gov/pubmed/17587447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-106 |
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