The catalytic subunit of the DNA polymerase of herpes simplex virus type 1 interacts specifically with the C terminus of the UL8 component of the viral helicase-primase complex.

The herpes simplex virus type 1 (HSV-1) UL8 DNA replication protein is a component of a trimeric helicase-primase complex. Sixteen UL8-specific monoclonal antibodies (MAbs) were isolated and characterized. In initial immunoprecipitation experiments, one of these, MAb 804, was shown to coprecipitate...

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Autors principals: Marsden, H S, McLean, G W, Barnard, E C, Francis, G J, MacEachran, K, Murphy, M, McVey, G, Cross, A, Abbotts, A P, Stow, N D
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC191912/
https://ncbi.nlm.nih.gov/pubmed/9261356
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