Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.

The vpr gene product of human immunodeficiency virus type 1 (HIV-1) is a virion-associated protein that is essential for efficient viral replication in monocytes/macrophages. Vpr is primarily localized in the nucleus when expressed in the absence of other viral proteins. Vpr is packaged efficiently...

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Bibliografski detalji
Izdano u:	J Virol
Glavni autori:	Mahalingam, S, Ayyavoo, V, Patel, M, Kieber-Emmons, T, Weiner, D B
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1997
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261351/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6339-6347.1997
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Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.

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