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The frequency of the C854 mutation in the aspartoacylase gene in Ashkenazi Jews in Israel.

Canavan disease (CD) is an infantile neurodegenerative disease that is transmitted in an autosomal recessive manner and has mainly been reported in Ashkenazi Jewish families. The primary enzymatic defect is aspartoacylase deficiency, and an A-to-C transition at nucleotide 854 of the cDNA has recentl...

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Главные авторы: Elpeleg, O. N., Anikster, Y., Barash, V., Branski, D., Shaag, A.
Формат: Artigo
Язык:Inglês
Опубликовано: 1994
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1918378/
https://ncbi.nlm.nih.gov/pubmed/8037206
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