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The Apolipoprotein E/CI/CII Gene Cluster and Late-Onset Alzheimer Disease

The chromosome 19 apolipoprotein E/CI/CII gene cluster was examined for evidence of linkage to a familial Alzheimer disease (FAD) locus. The family groups studied were Volga German (VG), early-onset non-VG (ENVG; mean age at onset <60 years), and late-onset families. A genetic association was obs...

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Autori principali: Yu, Chang-En, Payami, Haydeh, Olson, Jane M., Boehnke, Michael, Wijsman, Ellen M., Orr, Harry T., Kukull, Walter A., Goddard, Katrina A. B., Nemens, Ellen, White, June A., Alonso, M. Elisa, Taylor, Todd D., Ball, Melvyn J., Kaye, Jeffrey, Morris, John, Chui, Helena, Sadovnick, Adele D., Martin, George M., Larson, Eric B., Heston, Leonard L., Bird, Thomas D., Schellenberg, Gerard D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1918105/
https://ncbi.nlm.nih.gov/pubmed/8128960
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