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Modulation by endothelium of the responses induced by endothelin-1 and by some of its analogues in rat isolated aorta.

1. The contractile effects of endothelin-1 and various analogues were studied in rat isolated rings. The potency of the peptides studied was endothelin-1 greater than sarafotoxin S6b greater than [Ala3,11]endothelin-1 greater than [Ala1,15]endothelin-1. [Ala1,3,11,15]endothelin-1 was neither agonist...

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Bibliographic Details
Main Authors: Topouzis, S., Huggins, J. P., Pelton, J. T., Miller, R. C.
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1918046/
https://ncbi.nlm.nih.gov/pubmed/2015428
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