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Effects of glibenclamide on cytosolic calcium concentrations and on contraction of the rabbit aorta.

1. Using fluorometry of fura-2 and rabbit aortic strips, we studied the effects of glibenclamide (GLB), a sulphonylurea anti-diabetic drug and an inhibitor of opening of K+ channels, on cytosolic calcium concentrations ([Ca2+]i) and on force development. 2. Both high K(+)-depolarization and noradren...

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Detalhes bibliográficos
Main Authors: Yoshitake, K., Hirano, K., Kanaide, H.
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917894/
https://ncbi.nlm.nih.gov/pubmed/1904292
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