Octimibate, a potent non-prostanoid inhibitor of platelet aggregation, acts via the prostacyclin receptor

1 Octimibate, 8-[(1,4,5-triphenyl-1H-imidazol-2-yl)oxy]octanoic acid, is reported to have antihrombotic properties, This is in addition to its antihyperlipidaemic effects which are due to inhibition of acyl-CoA:cholesterol acyltransferase (ACAT). The aim of this study was to investigate the mechanis...

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Auteurs principaux: Merritt, Janet E., Hallam, Trevor J., Brown, Anthony M., Boyfield, Isobel, Cooper, David G., Hickey, Deirdre M.B., Jaxa-Chamiec, Albert A., Kaumann, Alberto J., Keen, Mary, Kelly, Eamonn, Kozlowski, Ursula, Lynham, James A., Moores, Kitty E., Murray, Kenneth J., MacDermot, John, Rink, Timothy J.
Format: Artigo
Langue:Inglês
Publié: 1991
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Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917884/
https://ncbi.nlm.nih.gov/pubmed/1710526
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