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L-NG-nitro arginine methyl ester exhibits antinociceptive activity in the mouse.

1. L-NG-nitro arginine methyl ester (L-NAME, 1-75 mg kg-1) administered intraperitoneally (i.p.) elicits dose-related antinociception in the mouse assessed by the formalin-induced paw licking procedure. Antinociceptive activity is still present 24 h after injection. L-NAME (75 mg kg-1, i.p.) is also...

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Autors principals: Moore, P. K., Oluyomi, A. O., Babbedge, R. C., Wallace, P., Hart, S. L.
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917872/
https://ncbi.nlm.nih.gov/pubmed/2043923
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