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Endotoxin-induced impairment of vasopressor and vasodepressor responses in the pithed rat.

1. Effects of E. coli endotoxin on vascular responsiveness to a variety of agents were compared with those of the calcium channel blocking drug nicardipine in pithed rats. 2. Infusion of endotoxin (250 micrograms kg-1 h-1) produced a fall in mean arterial blood pressure (8 mmHg). A similar fall (11...

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Autori principali: Guc, M. O., Furman, B. L., Parratt, J. R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917856/
https://ncbi.nlm.nih.gov/pubmed/2085714
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