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Theiler's virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 mice.

C57BL/6 mice develop a virus-specific cytotoxic T-lymphocyte (CTL) response after intraperitoneal inoculation with either the DA strain of Theiler's virus or Mengo virus, two members of the Cardiovirus genus. These CTLs contribute to viral clearance in the case of Theiler's virus but do not protect...

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Published in:J Virol
Main Authors: Dethlefs, S, Escriou, N, Brahic, M, van der Werf, S, Larsson-Sciard, E L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188606/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5361-5365.1997
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