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Pharmacological and biochemical comparison of thyrotropin releasing hormone (TRH) and di-methyl proline-TRH on pituitary GH3 cells.

1. The binding of [3H]-thyrotropin releasing hormone ([3H]-TRH) and [3H]-RX77368 (di-methyl proline TRH) and the ability of these peptides to stimulate phosphoinositide hydrolysis were investigated in the GH3 pituitary cell line. 2. For both peptides binding was found to be saturable with a single c...

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Detalhes bibliográficos
Main Authors: McDermott, A. M., Wilkin, G. P., Dickinson, S. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917728/
https://ncbi.nlm.nih.gov/pubmed/1963801
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