Inhibition of endothelial-bound angiotensin converting enzyme, in vivo.

1. We determined apparent Ki constants of two inhibitors, captopril and CL242,817, for pulmonary endothelial-bound angiotensin converting enzyme (ACE) in anaesthetized rabbits. [3H]-benzoyl-Phe-Ala-Pro was used as the substrate. The apparent kinetic parameters Km and Amax (product of Vmax and microv...

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Bibliografske podrobnosti
Main Authors: Catravas, J. D., Ryan, J. W., Chung, A. Y., Quinn, N. E., Anthony, B. L.
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917633/
https://ncbi.nlm.nih.gov/pubmed/2282454
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