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The 'calcium sensitising' effects of ORG30029 in saponin- or Triton-skinned rat cardiac muscle.

1. The effects of a range of concentrations of ORG30029 (1 microM to 1 mM) were investigated on fully (Triton-treated) or selectively (saponin-treated) 'skinned' ventricle trabeculae from rat. The Ca-sensitivity was increased by 100 microM and amounted to a mean reduction in the Ca2+ neces...

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Detalhes bibliográficos
Main Authors: Miller, D. J., Steele, D. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917589/
https://ncbi.nlm.nih.gov/pubmed/2207503
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