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Rapid tolerance to the hypotensive effects of glyceryl trinitrate in the rat: prevention by N-acetyl-L- but not N-acetyl-D-cysteine.

1. A new model of tolerance to the hypotensive effect of organic nitrates has been developed in the rat. 2. The fall in mean arterial pressure (MAP) in response to bolus doses of sodium nitroprusside (NP) (4 micrograms kg-1) and glyceryl trinitrate (GTN) (10 micrograms kg-1) was recorded both before...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Newman, C. M., Warren, J. B., Taylor, G. W., Boobis, A. R., Davies, D. S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1990
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917555/
https://ncbi.nlm.nih.gov/pubmed/2113825
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