CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activity

1 The pharmacological properties of CGP 37849 (DL-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid; 4-methyl-APPA) and its carboxyethylester, CGP 39551, novel unsaturated analogues of the N-methyl-D-aspartate (NMDA) receptor antagonist, 2-amino-5-phosphonopentanoate (AP5), were evaluated in rodent...

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Autores principales: Fagg, G.E., Olpe, H.-R., Pozza, M.F., Baud, J., Steinmann, M., Schmutz, M., Portet, C., Baumann, P., Thedinga, K., Bittiger, H., Allgeier, H., Heckendorn, R., Angst, C., Brundish, D., Dingwall, J.G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917531/
https://ncbi.nlm.nih.gov/pubmed/1972895
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