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Inhibitory effects of MK-886 on arachidonic acid metabolism in human phagocytes.

1. We have investigated the inhibitory activity of compound MK-886 (formerly L-663,536), an indole derivative, on 5-lipoxygenase product synthesis in various human phagocytes stimulated with either the ionophore A23187, in the presence and absence of exogenous arachidonic acid, or platelet-activatin...

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Bibliografische gegevens
Hoofdauteurs: Ménard, L., Pilote, S., Naccache, P. H., Laviolette, M., Borgeat, P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917464/
https://ncbi.nlm.nih.gov/pubmed/2164857
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