Tissue culture adaptation of foot-and-mouth disease virus selects viruses that bind to heparin and are attenuated in cattle.

Isolates of foot-and-mouth disease virus (FMDV) exist as complex mixtures of variants. Two different serotype O1 Campos preparations that we examined contained two variants with distinct plaque morphologies on BHK cells: a small, clear-plaque virus that replicates in BHK and CHO cells, and a large,...

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Bibliographic Details
Main Authors: Sa-Carvalho, D, Rieder, E, Baxt, B, Rodarte, R, Tanuri, A, Mason, P W
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191746/
https://ncbi.nlm.nih.gov/pubmed/9188578
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