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Glibenclamide is a competitive antagonist of the thromboxane A2 receptor in dog coronary artery in vitro.

1. Glibenclamide, a sulphonylurea oral hypoglycaemic agent is a widely used antagonist of cromakalim-activated K+ channels in smooth muscle. 2. In isolated ring segments of the large circumflex coronary artery from the dog, glibenclamide (1-30 microM) caused a concentration-dependent reduction in bo...

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Hlavní autoři: Cocks, T. M., King, S. J., Angus, J. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917442/
https://ncbi.nlm.nih.gov/pubmed/2143093
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