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Characterization of responses to cromakalim and pinacidil in smooth and cardiac muscle by use of selective antagonists.

1. In dog isolated coronary artery (precontracted with endothelin, 10 nM) cromakalim (0.1-30 microM) and pinacidil (1-30 microM) produced concentration-dependent vasorelaxant responses. The effects of these compounds could be blocked by glibenclamide (3 microM), phentolamine (30 microM) or alinidine...

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Bibliografiske detaljer
Main Authors: McPherson, G. A., Angus, J. A.
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917438/
https://ncbi.nlm.nih.gov/pubmed/2116201
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