Responses of rat substantia nigra compacta neurones to L-DOPA.

1. The electrophysiological actions of L-DOPA were studied on substantia nigra dopamine-containing neurones by use of intracellular recordings, current and voltage clamp, in vitro. 2. L-DOPA (3-300 microM), applied by superfusion, decreased the spontaneous firing activity of the neurones, hyperpolar...

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Bibliographic Details
Main Authors: Mercuri, N. B., Calabresi, P., Bernardi, G.
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917416/
https://ncbi.nlm.nih.gov/pubmed/2165836
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