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The mechanism of action of the optical enantiomers of verapamil against ischaemia-induced arrhythmias in the conscious rat.

The actions of (-)-verapamil (0.2-6 mg kg-1) and (+)-verapamil (0.4-12 mg kg-1) against arrhythmias induced by coronary artery occlusion were studied in conscious rats. Intravenously administered (-)- and (+)-verapamil dose-dependently reduced ventricular arrhythmias. (-)-Verapamil was consistently...

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Bibliografische gegevens
Hoofdauteurs: Curtis, M. J., Walker, M. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917029/
https://ncbi.nlm.nih.gov/pubmed/3801768
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