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Probenecid potentiates the hyperglycaemic effect but reduces the diuretic effect of frusemide in mice.
The effect of probenecid on frusemide-induced diuresis and hyperglycaemia was studied in mice. Probenecid, a known inhibitor of tubular secretion of organic anions in the kidney, strongly reduced the diuretic response to frusemide (25 or 200 mg kg-1 body weight). This effect of probenecid appeared t...
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Formatua: | Artigo |
Hizkuntza: | Inglês |
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1986
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Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1917023/ https://ncbi.nlm.nih.gov/pubmed/3779212 |
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