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Probenecid potentiates the hyperglycaemic effect but reduces the diuretic effect of frusemide in mice.

The effect of probenecid on frusemide-induced diuresis and hyperglycaemia was studied in mice. Probenecid, a known inhibitor of tubular secretion of organic anions in the kidney, strongly reduced the diuretic response to frusemide (25 or 200 mg kg-1 body weight). This effect of probenecid appeared t...

詳細記述

保存先:
書誌詳細
第一著者: Sandström, P. E.
フォーマット: Artigo
言語:Inglês
出版事項: 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917023/
https://ncbi.nlm.nih.gov/pubmed/3779212
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