Diminishing adenovirus gene expression and viral replication by promoter replacement.
The adenovirus E4 promoter was replaced by a synthetic promoter composed of a minimal TATA box and five consensus 17-mer yeast GAL4-binding-site elements. The viral vectors, which also contained human factor IX (hFIX) cDNA driven by Rous sarcoma virus long terminal repeat in the E1 region, were then...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191702/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4798-4803.1997 |
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