Herpes simplex virus type 1 prereplicative sites are a heterogeneous population: only a subset are likely to be precursors to replication compartments.

When herpes simplex virus type 1 (HSV-1) DNA replication is blocked by viral polymerase inhibitors, such as phosphonoacetic acid (PAA) or acyclovir (ACV), UL29 (ICP8) localizes to numerous punctate nuclear foci which are called prereplicative sites. Since this pattern can form in cells infected with...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lukonis, C J, Burkham, J, Weller, S K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4771-4781.1997
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