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Inhibition of cisplatin-induced vomiting by selective 5-hydroxytryptamine M-receptor antagonism.

MDL 72222, the selective 5-hydroxytryptamine (5-HT) M-receptor antagonist, prevented or reduced cisplatin-induced emesis in ferrets. It is suggested that cisplatin-induced, and possibly other cytotoxic drug-induced vomiting may involve a 5-HT M-receptor mechanism.

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Bibliografische gegevens
Hoofdauteurs: Miner, W. D., Sanger, G. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1916988/
https://ncbi.nlm.nih.gov/pubmed/3742146
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