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Convulsant doses of penicillin shorten the lifetime of GABA-induced channels in cultured central neurones.
The influence of sodium benzylpenicillin (PCN) on membrane channels activated by gamma-aminobutyric acid (GABA) was studied in cultured spinal neurones of the mouse by the extracellular patch clamp technique. In whole-cell, current clamp recordings, concentrations of PCN above 0.2 mM significantly r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1916982/ https://ncbi.nlm.nih.gov/pubmed/2427143 |
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