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Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes.

Infection of B lymphocytes by Epstein-Barr virus (EBV) requires attachment of virus via binding of viral glycoprotein gp350 to CD21 on the cell surface. Penetration of the cell membrane additionally involves a complex of three glycoproteins, gH, gL, and gp42. Glycoprotein gp42 binds to HLA-DR. Inter...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphov: Li, Q, Spriggs, M K, Kovats, S, Turk, S M, Comeau, M R, Nepom, B, Hutt-Fletcher, L M
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151859/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4657-4662.1997
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