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The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells.

The major immediate-early (MIE) gene products of human cytomegalovirus (HCMV) are nuclear phosphoproteins that are thought to play key roles in initiating lytic cycle gene regulation pathways. We have examined the intranuclear localization pattern of both the IE1 and IE2 proteins in virus-infected a...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Ahn, J H, Hayward, G S
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191682/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4599-4613.1997
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