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Prostaglandin endoperoxide analogues which are both thromboxane receptor antagonists and prostacyclin mimetics.

Two prostaglandin endoperoxide analogues, EP 035 and EP 157, behave as specific thromboxane receptor antagonists on isolated smooth muscle preparations such as rabbit aorta, dog saphenous vein and guinea-pig trachea. However, in human platelet-rich plasma (PRP) they produce an unsurmountable block o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Armstrong, R. A., Jones, R. L., MacDermot, J., Wilson, N. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1916575/
https://ncbi.nlm.nih.gov/pubmed/3026540
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