The antiretrovirus drug 3'-azido-3'-deoxythymidine increases the retrovirus mutation rate.

It was previously observed that the nucleoside analog 5-azacytidine increased the spleen necrosis virus (SNV) mutation rate 13-fold in one cycle of retrovirus replication (V. K. Pathak and H. M. Temin, J. Virol. 66:3093-3100, 1992). Based on this observation, we hypothesized that nucleoside analogs...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Julias, J G, Kim, T, Arnold, G, Pathak, V K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4254-4263.1997
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