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Estrogen-induced hyperplasia and neoplasia in the rat anterior pituitary gland. An immunohistochemical study.

Diethylstilbestrol (DES) treatment of weanling F344 female rats resulted in enlarged pituitary glands and diffuse pituitary prolactin (PRL) cell hyperplasia in all animals after 9 and 12 weeks of treatment. Serum PRL was significantly greater than in control rats (P less than 0.001). Immunohistochem...

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Detalhes bibliográficos
Autor principal: Lloyd, R. V.
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1916372/
https://ncbi.nlm.nih.gov/pubmed/6638150
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