Synergistic inhibition of replication of human immunodeficiency virus type 1, including that of a zidovudine-resistant isolate, by zidovudine and 2',3'-dideoxycytidine in vitro.

The combination of zidovudine (AZT) and 2',3'-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 (HIV-1) replication in vitro with AZT-sensitive and AZT-resistant clinical isolates and HIV-1IIIB. Synergy was determined by the median-effect principle and isobologram techniqu...

Description complète

Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Eron, J J, Johnson, V A, Merrill, D P, Chou, T C, Hirsch, M S
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1324648/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.7.1559
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!