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Simulation of human serum pharmacokinetics of cefazolin, piperacillin, and BRL 42715 in rats and efficacy against experimental intraperitoneal infections.

Studies were performed to determine the effects of BRL 42715, a potent beta-lactamase inhibitor, on the activity of cefazolin and piperacillin against experimental intraperitoneal infections caused by either Escherichia coli or Serratia marcescens in rats. Compounds were administered to rats as a co...

Повний опис

Збережено в:
Бібліографічні деталі
Опубліковано в::Antimicrob Agents Chemother
Автори: Woodnutt, G, Berry, V, Mizen, L
Формат: Artigo
Мова:Inglês
Опубліковано: American Society for Microbiology (ASM) 1992
Предмети:
Онлайн доступ:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510438/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.7.1427
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