Pharmacokinetics of imipenem in serum and skin window fluid in healthy adults after intramuscular or intravenous administration.

The pharmacokinetic profiles of imipenem after intramuscular (i.m.) and intravenous injections were examined in adult volunteers. Levels of imipenem in serum after i.m. injection of a microcrystalline suspension of imipenem-cilastatin (500 mg each) reached a peak (8.0 micrograms/ml) at 1.5 h after a...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Signs, S A, Tan, J S, Salstrom, S J, File, T M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510434/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.7.1400
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