Negative chronotropic and inotropic effects exerted by diadenosine hexaphosphate (AP6A) via A1-adenosine receptors.

1. Diadenosine hexaphosphate (AP6A) exerts vasoconstrictive effects. The purpose of this study was to investigate whether AP6A has any effect on cardiac function. 2. The effects of AP6A (0.1-100 microM) on cardiac contractility and frequency were studied in guinea-pig and human isolated cardiac prep...

詳細記述

保存先:
書誌詳細
主要な著者: Vahlensieck, U., Bokník, P., Knapp, J., Linck, B., Müller, F. U., Neumann, J., Herzig, S., Schlüter, H., Zidek, W., Deng, M. C., Scheld, H. H., Schmitz, W.
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915918/
https://ncbi.nlm.nih.gov/pubmed/8922729
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