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A novel GTP-dependent mechanism of ileal muscarinic metabotropic channel desensitization.

1. Cationic current (Icat) was evoked in single isolated smooth muscle cells either by activating muscarinic receptors with the stable muscarinic agonist, carbachol (CCh), or by dialysing cells with GTP-gamma S. It was studied using patch-clamp recording techniques in cells obtained by enzymatic dig...

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Autores principales: Zholos, A. V., Bolton, T. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915917/
https://ncbi.nlm.nih.gov/pubmed/8922752
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